Top 10 Safest Companies To Own In Right Now

European stocks have done well in 2013. The Vanguard FTSE Europe ETF and iShares Europe ETF may still be good bets.

NEW YORK (CNNMoney) Stocks are surging in the United States this year. Japan has done even better.

But if you're looking for the next big opportunity, Europe could very well be the best place to invest right now. The long recession in Europe may finally be over. And that could lead to stronger profits from European-based companies.

So what's the safest way to try and ride a European rebound?

Investing through a mutual fund: Many funds from big money managers have a fair amount of European exposure.

Take the widely held Fidelity Worldwide Fund (FWWFX), which has 30% of its assets invested in Europe. Holdings include Swiss bank UBS (UBS), German automaker Volkswagen (VLKAY) and French food and consumer products giant Danone (DANOY).

Hot High Tech Companies To Watch For 2015: Cell Therapeutics Inc (CTIC)

Cell Therapeutics, Inc. (CTI), incorporated in 1991, develops, acquires and commercializes treatments for cancer. The Company�� research, development, acquisition and in-licensing activities concentrate on identifying and developing new ways to treat cancer. As of December 31, 2011, CTI focused its efforts on Pixuvri (pixantrone dimaleate) (Pixuvri), OPAXIO (paclitaxel poliglumex) (OPAXIO), tosedostat, brostallicin and bisplatinates. As of December 31, 2011, it developed Pixuvri, an anthracycline derivative for the treatment of hematologic malignancies and solid tumors. Another late-stage drug candidate of the Company, OPAXIO, is being studied as a potential maintenance therapy for women with advanced stage ovarian cancer, who achieve a complete remission following first-line therapy with paclitaxel and carboplatin. As of December 31, 2011, it also developed tosedostat in collaboration with Chroma Therapeutics, Ltd. (Chroma). On May 31, 2012, CTI completed its acquisition gaining worldwide rights to S*BIO Pte Ltd.'s (S*BIO) pacritinib.

Pixuvri

As of December 31, 2011, the Company developed Pixuvri, an aza-anthracenedione derivative, for the treatment of non-Hodgkin�� lymphoma (NHL), and various other hematologic malignancies, and solid tumors. Pixuvri was studied in the Company�� EXTEND, or PIX301, clinical trial, which was a phase III single-agent trial of Pixuvri for patients with relapsed, refractory aggressive NHL who received two or more prior therapies and who were sensitive to treatment with anthracyclines. On September 28, 2011, CTI announced that a second independent radiology assessment of response and progression endpoint data from its PIX301 clinical trial of Pixuvri was achieved with statistical significance. The results of the EXTEND trial met its primary endpoint and showed that patients randomized to treatment with Pixuvri achieved a significantly higher rate of confirmed and unconfirmed complete response compared to patients treated with standard chem! otherapy had a significantly increased overall response rate and experienced a statistically significant improvement in median progression free survival. Pixuvri had predictable and manageable toxicities when administered at the proposed dose and schedule in the EXTEND clinical trial in heavily pre-treated patients. In March 2011, the Company initiated the PIX-R trial to study Pixuvri in combination with rituximab in patients with relapsed/refractory diffuse large B-cell lymphoma (DLBCL). Pixuvri has also been studied in patients with HER2-negative metastatic breast cancer who have tumor progression after at least two, but not more than three, prior chemotherapy regimens. In the second quarter of 2010, the NCCTG opened this phase II study for enrollment. The study is closed to accrual and results are expected to be reported by the NCCTG later in 2012.

OPAXIO

OPAXIO is the Company�� biologically-enhanced chemotherapeutic agent that links paclitaxel to a biodegradable polyglutamate polymer, resulting in a new chemical entity. As of December 31, 2011, the Company focused its development of OPAXIO on ovarian, brain, esophageal, head and neck cancer. OPAXIO was designed to improve the delivery of paclitaxel to tumor tissue while protecting normal tissue from toxic side effects. In November 2010, results were presented by the Brown University Oncology Group from a phase II trial of OPAXIO combined with temozolomide (TMZ), and radiotherapy in patients with newly-diagnosed, high-grade gliomas, a type of brain cancer. The trial demonstrated a high rate of complete and partial responses and a high rate of six month progression free survival (PFS). Based on these results, the Brown University Oncology Group has initiated a randomized, multicenter, phase II study of OPAXIO and standard radiotherapy versus TMZ and radiotherapy for newly diagnosed patients with glioblastoma with an active gene termed MGMT that reduces responsiveness to TMZ. A phase I/II study of OPAXIO combined with radi! otherapy ! and cisplatin was initiated by SUNY Upstate Medical University, in patients with locally advanced head and neck cancer.

Tosedostat

In March 2011, the Company entered into a co-development and license agreement with Chroma Therapeutics, Ltd. (Chroma), providing the Company with marketing and co-development rights to Chroma�� drug candidate, tosedostat, in North, Central and South America. Tosedostat is an oral, aminopeptidase inhibitor that has demonstrated anti-tumor responses in blood related cancers and solid tumors in phase I-II clinical trials. Interim results from the phase II OPAL study of tosedostat in elderly patients with relapsed or refractory acute myeloid leukemia (AML) showed that once-daily, oral doses of tosedostat had predictable and manageable toxicities and results demonstrated response rates, including a high-response rate among patients who received prior hypomethylating agents, which are used to treat myelodysplastic syndrome (MDS), a precursor of AML.

Brostallicin

As of December 31, 2011, the Company developed brostallicin through its wholly owned subsidiary, Systems Medicine LLC, which holds rights to use, develop, import and export brostallicin. Brostallicin is a synthetic deoxyribonucleic acid (DNA) minor groove binding agent that has demonstrated anti-tumor activity and a favorable safety profile in clinical trials, in which more than 230 patients have been treated as of December 31, 2011. The Company uses a genomic-based platform to guide the development of brostallicin. A phase II study of brostallicin in relapsed, refractory soft tissue sarcoma met its predefined activity and safety hurdles and resulted in a first-line phase II clinical trial study that was conducted by the European Organization for Research and Treatment of Cancer (EORTC).

The Company competes with Bristol-Myers Squibb Company, Sanofi-Aventis, Pfizer, Roche Group, Genentech, Inc., Astellas Pharma, Eli Lilly and Company, Celgene, Telik, I! nc., TEVA! Pharmaceuticals Industries Ltd. and PharmaMar.

Advisors' Opinion:

• [By John Udovich]

  Large and small cap cancer stocks Gilead Sciences, Inc (NASDAQ: GILD), Celgene Corporation (NASDAQ: CELG), Veracyte (NASDAQ: VCYT), Genomic Health, Inc (NASDAQ: GHDX), Cell Therapeutics Inc (NASDAQ: CTIC) and MetaStat Inc (OTCMKTS: MTST) have all been producing a steady stream of news lately for biotech investors looking for a way to cash in on the growth in development of�cancer treatments. Just consider the following news:

• [By Sean Williams]

  Cell Therapeutics (NASDAQ: CTIC  )
  Certainly no discussion of companies with large accumulated deficits would be complete without discussing a biotechnology company. It's perfectly understandable to see a biotech, especially a clinical-stage one, run with an accumulated deficit, as it takes time and money to build up a drug pipeline. However, after multiple complete response letters (the equivalent of a rejection) by the Food and Drug Administration and years without an approved drug, Cell Therapeutics racked up an astounding $1.83 billion in accumulated deficits through the end of fiscal 2012. By comparison, that's nearly 56 times larger than its shareholder equity.�

Top 10 Safest Companies To Own In Right Now: CVR Energy Inc (CVI)

CVR Energy, Inc. (CVR Energy), incorporated September 2006, through its wholly owned subsidiaries, acts as an independent petroleum refiner and marketer of transportation fuels in the mid-continental United States. In addition, the Company, through its majority-owned subsidiaries, acts as an independent producer and marketer of nitrogen fertilizer products in North America. As of December 31, 2011, the Company owned the general partner and approximately 70% of CVR Partners, LP (the Partnership), a limited partnership which produces nitrogen fertilizers in the form of ammonia and an aqueous solution of urea and ammonium nitrate used as a fertilizer (UAN). The Company operates in two segments: the petroleum segment and the nitrogen fertilizer segment. On December 15, 2011, the Company acquired Gary-Williams Energy Corporation and its subsidiaries (GWEC).

Petroleum Business

The Company operates a 115,000 barrels per day complex full coking medium-sour crude oil refinery in Coffeyville, Kansas and, as of December 15, 2011, a 70,000 barrels per day crude oil unit refinery in Wynnewood, Oklahoma. Its combined production capacity represents approximately 15% of its region's output during the year ended December 31, 2011. The Coffeyville facility is situated on approximately 440 acres in southeast Kansas, approximately 100 miles from Cushing, Oklahoma, a crude oil trading and storage hub. The Wynnewood facility is situated on approximately 400 acres located approximately 65 miles south of Oklahoma City, Oklahoma and approximately 130 miles from Cushing, Oklahoma. During 2011, its Coffeyville refinery's product yield included gasoline (mainly regular unleaded) (44%), diesel fuel (42%), and pet coke and other refined products, such as natural gas liquids (NGL) (propane and butane), slurry, sulfur and gas oil (14%). Its Wynnewood refinery's product yield included gasoline (54%), diesel fuel (31%), asphalt (6%), jet fuel (3%) and other products (6%) during 2011.

The Company! owns and operates a crude oil gathering system serving Kansas, Oklahoma, western Missouri and southwestern Nebraska. The system has field offices in Bartlesville, Oklahoma, Plainville, Kansas and Winfield, Kansas. The system consists of approximately 350 miles of feeder and trunk pipelines, 100 trucks, and associated storage facilities for gathering sweet crude oils purchased from independent crude oil producers in Kansas, Nebraska, Oklahoma and Missouri. It also leases a section of a pipeline from Magellan Midstream Partners, L.P. (Magellan), which is incorporated into its crude oil gathering system. During 2011, the Company�� crude oil gathering system had a gathering capacity of approximately 38,000 barrels per day. During 2011, it gathered an average of approximately 35,000 barrels per day.

CVR Energy owns a pipeline system capable of transporting approximately 145,000 barrels per day of crude oil from Caney, Kansas to its refinery. Crude oils sourced outside of its gathering system are delivered by common carrier pipelines into various terminals in Cushing, Oklahoma, where they are blended and then delivered to Caney, Kansas via a pipeline owned by Plains Pipeline L.P. (Plains). The Company also owns associated crude oil storage tanks with a capacity of approximately 1.2 million barrels located outside its Coffeyville refinery, 0.5 million barrels of crude oil storage at Wynnewood, Oklahoma, and lease an additional 3.3 million barrels of storage capacity located at Cushing, Oklahoma and other locations. In addition to crude oil storage, it owns approximately 4.5 million barrels of combined refinery related storage capacity.

CVR Energy has access to foreign crude oil from Latin America, South America, West Africa, the Middle East, the North Sea and Canada. It purchases domestic crude oil from Kansas, Oklahoma, Nebraska, Texas, North Dakota, Missouri, and offshore deepwater Gulf of Mexico production. During 2011, its Coffeyville crude oil supply blend consisted of approx! imately 8! 0% light sweet crude oil, 2% light/medium sour crude oil and 18% heavy sour crude oil. During 2011, Wynnewood's crude oil supply blend consisted of approximately 88% sweet crude oil and 12% light/medium sour crude oil.

During 2011, approximately 35% of the Coffeyville refinery's products were sold through the rack system directly to retail and wholesale customers, while the remaining 65% was sold through pipelines via bulk spot and term contracts. The Company makes bulk sales (sales into third party pipelines) into the mid-continent markets via Magellan and into Colorado and other destinations utilizing the product pipeline networks owned by Magellan, Enterprise Products Operating, L.P. (Enterprise) and NuStar Energy, LP (NuStar). Approximately 60% of the Wynnewood refinery's finished products sold are distributed in Oklahoma. Customers for its petroleum products include other refiners, convenience store companies, railroads and farm cooperatives.

The Company competes with BP, Conoco Phillips, HollyFrontier, NCRA, Valero, Flint Hills Resources, CHS and Shell.

Nitrogen Fertilizer Business

The nitrogen fertilizer business, operated by the Partnership, is the nitrogen fertilizer plant in North America. It utilizes a pet coke gasification process to produce nitrogen fertilizer. The nitrogen fertilizer facility's primary input is pet coke. The nitrogen fertilizer facility includes a 1,225 ton-per-day ammonia unit, a 2,025 ton-per-day UAN unit and a gasifier complex having a capacity of 84 million standard cubic feet per day. Linde LLC (Linde) owns, operates, and maintains the air separation plant that provides contract volumes of oxygen, nitrogen and compressed dry air to the gasifier for a monthly fee.

The primary geographic markets for the nitrogen fertilizer business' fertilizer products are Kansas, Missouri, Nebraska, Iowa, Illinois, Colorado and Texas. The nitrogen fertilizer business markets the ammonia products to industrial and agricu! ltural cu! stomers and the UAN products to agricultural customers. The nitrogen fertilizer business sells ammonia to agricultural and industrial customers. Agricultural customers include distributors such as MFA, United Suppliers, Inc., Brandt Consolidated Inc., Gavilon Fertilizer LLC, Transammonia, Inc., Agri Services of Brunswick, LLC, Interchem and CHS Inc. Industrial customers include Tessenderlo Kerley, Inc., National Cooperative Refinery Association, and Dyno Nobel, Inc. The nitrogen fertilizer business sells UAN products to retailers and distributors.

The Company competes with Agrium, Koch Nitrogen, Potash Corporation and CF Industries.

Advisors' Opinion:

• [By Hibah Yousuf]

  Snyder also pointed out that Take-Two was not that big of a holding for Icahn. It represented less than 1% of Icahn Enterprise's (IEP, Fortune 500) total portfolio. The firms' largest holdings include CVR Energy (CVI), Apple (AAPL, Fortune 500), Chesapeake Energy (CHK, Fortune 500) and Herbalife (HLF).

• [By Aimee Duffy]

  1. CVR Refining (NYSE: CVRR  ) -- 22.5% yield
  As its name suggests, CVR Refining is a downstream master limited partnership in the CVR Energy (NYSE: CVI  ) family. It controls two refineries, one in Kansas and one in Oklahoma, as well as a pipeline and storage network.

Top 10 Safest Companies To Own In Right Now: MRC Global Inc (MRC)

MRC Global Inc., formerly known as McJunkin Red Man Holding Corporation, incorporated on November 20, 2006, is a holding company. The Company is the distributor of pipe, valves and fittings (PVF) and related products and services to the energy industry. The Company offers a range of PVF and oilfield supplies encompassing a complete line of products from its global network of suppliers to its more than 12,000 customers. The Company operates in two segments: North American segment and International segment. Its North American segment includes over 180 branch locations, six distribution centers in the United States, one distribution center in Canada, 11 valve automation service centers and over 170 pipe yards located in the oil and natural gas regions in North America. Its International segment includes over 40 branch locations throughout Europe, Asia and Australasia with distribution centers in each of the United Kingdom, Singapore and Australia and 10 automation service centers in Europe and Asia. On June 9, 2011, it acquired Stainless Pipe and Fittings Australia Pty. Ltd. (MRC SPF). On July 22, 2011, it acquired Valve Systems and Controls (VSC). In January 2013, the Company's subsidiary, McJunkin Red Man Corporation,acquired operating assets of Production Specialty Services, Inc. In July 2013, MRC Global Inc announced that it has completed the previously announced acquisition of the operating assets of Dan H. Brown, Inc., D/B/A Flow Control Products (Flow Control). In December 2013, MRC Global Inc acquired Flangefitt Stainless Ltd. Effective January 6, 2014, MRC Global Inc a unit of GS Capital Partners LP subsidiary of Goldman Sachs Group Inc's Goldman Sachs & Co unit, acquired Stream AS.

The Company distributes products globally, including in PVF intensive, oil and natural gas exploration and production (E&P) areas, such as the Bakken, Barnett, Eagle Ford, Fayetteville, Haynesville, Marcellus, Niobrara and Utica shales in North America. Its Canadian subsidiary Midfield Supply ULC and its! subsidiaries (MRC Midfield), provides PVF products to oil and natural gas companies operating primarily in Western Canada, including the Western Canadian Sedimentary Basin, Alberta Oil Sands and heavy oil regions. It offers more than 150,000 stock keeping units (SKUs), including a range of PVF, oilfield supply, automation, instrumentation and other general and specialty industry supply products.

The Company is the majority owned subsidiary of PVF Holdings LLC. Its wholly owned subsidiary, McJunkin Red Man Corporation and its subsidiaries (MRC), are global distributors of pipe, valves, fittings and related products and services across each of the upstream (exploration, production and extraction of underground oil and gas), midstream (gathering and transmission of oil and gas, gas utilities, and the storage and distribution of oil and gas) and downstream (crude oil refining, petrochemical processing and general industrials) markets. The Company serves the global oil and natural gas industry, generating approximately 90% of its sales from supplying products and services to customers throughout the energy industry. Of its total sales, 62% of sales are comprised of valves, fittings and flanges and other industrial supply products and 38% are tubular products, mainly line pipe and oil country tubular goods (OCTG) as of September 30, 2011.

North American Operations

The Company distributes PVF products, primarily used in applications in the energy infrastructure sector, from its global network of suppliers. The products it distributes are used in the construction, maintenance, repair and overhaul of equipments. The products include Valves and Specialty Products, Line Pipe, OCTG, Carbon Steel Fittings and Flanges and Stainless Steel and Alloy Pipe and Fittings and others. The products under valves and specialty products include ball, butterfly, gate, globe, check, needle and plug valves, which are manufactured from cast steel, stainless/alloy steel, forged steel, carbon st! eel or ca! st and ductile iron. Specialty products include lined corrosion resistant piping systems, valve automation and top work components used for regulating flow and on/off service, and a range of steam and instrumentation products used in various process applications within its refinery, petrochemical and general industrial sectors.

Carbon line pipe is used in high-yield, high-stress, abrasive applications, such as the gathering and transmission of oil, natural gas and phosphates. Line pipe is part of its tubular product category. OCTG is part of its tubular product category, includes casing (used for production and to line the well bore) and tubing pipe (used to extract oil or natural gas from wells) and is either classified as carbon or alloy depending on the grade of material. Carbon steel fittings and flanges include carbon weld fittings, flanges and piping components used primarily to connect piping and valve systems for the transmission of various liquids and gases. These products are used across all the industries in which it operates. Stainless steel and alloy pipe and fittings include stainless, alloy and corrosion resistant pipe, tubing, fittings and flanges. These are used in the chemical, refining and power generation industries, as well as across all of the sectors in which the Company operates. Alloy products are principally used in high-pressure, high-temperature and high-corrosion applications typically seen in process piping applications.

The products under other category include natural gas distribution products, oilfield supplies, and other industrial products, such as mill and safety and electrical supplies. Natural gas distribution products include risers, meters, polyethylene pipe and fittings and various other components and industrial supplies used primarily in the distribution of natural gas to residential and commercial customers. It offers a range of oilfield and industrial supplies and completion equipment, and products offered include high density polyet! hylene pi! pe and fittings, valves, well heads, pumping units and rods. In addition, it supplies a range of specialized production equipment, including meter runs, tanks and separators used in its upstream sector.

The Company provides its customers with a range of services, including multiple deliveries each day, zone store management, valve tagging and system interfaces that directly tie the customer into its information systems. Its information system, which provides for customer and supplier electronic integrations, information sharing and e-commerce applications, provides service to its customers. The Company sources the products it distributes from a global network of suppliers. The remainder of the products it distributes are sourced from manufacturer representatives, trading companies and, in some instances, other distributors.

The Company competes with Wilson Industries, Inc., National Oilwell Varco, Inc. and Ferguson Enterprises.

International Operations

The Company�� International segment represents its valve and stainless and alloy pipe, fitting and flange distribution business to the energy and general industrial sectors, across each of the downstream and upstream sectors, through its distribution operations located throughout Europe, Asia, Australasia and the Middle East. Through its over 40 branch and service facilities throughout Europe, Asia, Australasia and the Middle East, it distributes a complete line of valve and stainless and alloy pipe, fittings and flanges and specialty products. Its Valve products offered include ball, butterfly, gate, globe, check, needle and plug valves, which are manufactured from cast steel, stainless/alloy steel, forged steel, carbon steel or cast and ductile iron. Valves are used in oilfield and industrial applications to control direction, velocity and pressure of fluids and gases within transmission networks. Specialty products include lined corrosion resistant piping systems, valve automation and top work compo! nents use! d for regulating flow and on/off service and a range of steam and instrumentation products used in various process applications within its offshore, refinery, petrochemical and general industrial sectors.

Stainless steel products are used in all sectors in which it operates, including oil and gas, mining and mineral processing, water treatment and desalination, and petrochemical. It provides its customers with a range of services, including multiple daily deliveries, zone stores management, valve tagging and system interfaces that directly tie the customer into its information systems.

The Company competes with Econosto.

Advisors' Opinion:

• [By Monica Wolfe]

  MRC Global (MRC)

  Over the duration of the second quarter, Columbia Wanger upped their position in MRC Global by 258.43%. The fund purchased 1,809,000 shares of the company�� stock at an average price of $29.69. Since their increase, the price per share has dropped -18.9%.

• [By Eric Volkman]

  MRC Global (NYSE: MRC  ) now officially has a new asset in its portfolio. The company announced it has finalized the acquisition of the operating assets of Flow Control Products. It describes the once privately held firm as "a leading provider of pneumatic, electric and electro-hydraulic valve automation packages and related field support to the Permian Basin energy industry, including production facilities, pipelines, and plant operations." According to MRC Global, the company posted $28 million in revenues last year.

Top 10 Safest Companies To Own In Right Now: Consumer Portfolio Services Inc.(CPSS)

Consumer Portfolio Services, Inc. operates as a specialty finance company in the United States. It engages in purchasing and serving retail automobile contracts originated by franchised automobile dealers and select independent dealers in the sale of new and used automobiles, light trucks, and passenger vans. The company, through its automobile contract purchases, provides indirect financing to dealer customers for borrowers with limited credit histories, low incomes, or past credit problems. It serves as an alternative source of financing for dealers, allowing sales to customers who might not be able to obtain financing. The company also directly finances consumers for vehicle purchases. Consumer Portfolio Services, Inc. provides its automobile contracts through its headquarters and three servicing branches in Virginia, Florida, and Illinois. The company was founded in 1991 and is headquartered in Irvine, California.

Advisors' Opinion:

• [By Rick Munarriz]

  Finally, we have Consumer Portfolio Services (NASDAQ: CPSS  ) driving past where the pros were parked. Consumer Portfolio Services provides indirect automobile financing, primarily to folks with dodgy credit histories buying late-model used cars. This is a risky niche when the economy's souring, but business is booming these days.

Top 10 Safest Companies To Own In Right Now: Nanosphere Inc.(NSPH)

Nanosphere, Inc. develops, manufactures, and markets molecular diagnostics platform, the Verigene System that enables genomic and protein testing on a single platform. Its Verigene System includes a bench-top molecular diagnostics workstation with nanoparticle technology that provides the ability to run multiple tests simultaneously on the same sample. The Verigene System is used for testing infectious disease assays, human and pharmacogenetic assays, and ultra-sensitive protein assays. The company serves hospital-based laboratories and academic research institutions in the United States. Nanosphere, Inc. was founded in 1998 and is headquartered in Northbrook, Illinois.

Advisors' Opinion:

• [By Roberto Pedone]

  
  

  One under-$10 medical equipment player that's quickly moving within range of triggering a major breakout trade is Nanosphere (NSPH), which develops, manufactures and markets an advanced molecular diagnostics platform, the Verigene System, which enables simple, low-cost and highly sensitive genomic and protein testing on a single platform. This stock has been hit hard by the bears so far in 2013, with shares off by 27%.

  If you take a look at the chart for Nanosphere, you'll notice that this stock is just starting to spike sharply higher today back above its 50-day moving average of $2 a share. This spike is quickly pushing shares of NSPH within range of triggering a major breakout trade. That breakout will trigger once NSPH manages to take out the upper-end of its recent sideways trading chart pattern.

  Traders should now look for long-biased trades in NSPH if it manages to break out above some near-term overhead resistance levels at $2.17 to $2.20 a share and then once it takes out its gap down day high from August at $2.29 a share with high volume. Look for a sustained move or close above those levels with volume that hits near or above its three-month average action of 652,718 shares. If that breakout hits soon, then NSPH will set up to re-fill some of its previous gap down zone from August that stated just above $3 a share. If that gap gets filled with volume, then NSPH could easily tag $3.50 to $4 a share.

  Traders can look to buy NSPH off any weakness to anticipate that breakout and simply use a stop that sits right below some key near-term support levels at $1.81 to $1.77 a share. One can also buy NSPH off strength once it clears those resistance levels with volume and then simply use a stop that sits a comfortable percentage from your entry point.

• [By Jon C. Ogg]

  Nanosphere Inc. (NASDAQ: NSPH) is not exactly a household name in molecular diagnostics, and apparently it needs better name recognition for boosting sales. Its sales were disappointing and the stock was down almost 18% at $2.40, and now we have indications down around $2.35 in Wednesday trading indications.

Top 10 Safest Companies To Own In Right Now: GSI Group Inc.(GSIG)

GSI Group Inc. designs, develops, manufactures, and sells laser-based solutions, laser scanning devices, and precision motion and optical control technologies worldwide. The company?s Laser Products segment provides lasers and laser-based systems for photonics-based applications, such as cutting, welding, marking, engraving, micro-machining, and scientific research. Its Precision Motion and Technologies segment designs, manufactures, and markets air bearing spindles, encoders, thermal printers, laser scanning devices, and light and color measurement systems to original equipment manufacturers. The company?s Semiconductor Systems segment offers laser based production systems for semiconductor, microelectronics, and electronics manufacturing. This segment?s products comprise WaferRepair for dynamic random access memory, flash memory chips, and LCDs; WaferMark for silicon suppliers and integrated circuit factories; and WaferTrim and Circuit Trim for analog and mixed signal sensor and chip resistor devices, as well as for resistor devices. The company sells its products primarily through direct sales force, resellers, distributors, and system integrators. It serves industrial, electronics, automotive, medical, packaging, aerospace, scientific, semiconductor, lighting, military, and motion picture markets. The company was formerly known as GSI Lumonics Inc. and changed its name to GSI Group Inc. in 2005. GSI Group Inc. was founded in 1970 and is based in Bedford, Massachusetts.

Advisors' Opinion:

• [By Eric Volkman]

  Electro Scientific Industries (NASDAQ: ESIO  ) has a new division under its corporate wing. The company has inked a definitive agreement to purchase the semiconductor systems unit of GSI Group (NASDAQ: GSIG  ) . The terms of the deal were not disclosed.

Top 10 Safest Companies To Own In Right Now: Bridgeline Digital Inc.(BLIN)

Bridgeline Digital, Inc. engages in the development of Web experience management (WEM) product and interactive technology solutions that help organizations to optimize business processes. Its iAPPS product suite includes iAPPS Content Manager that allows non-technical users to create, edit, and publish content through a browser-based interface; iAPPS Commerce, an online B2B and B2C eCommerce solution, which allows users to maximize and manage various aspects of commerce initiatives; and iAPPS Marketier, a marketing lifecycle management solution that comprises customer transaction analysis, email management, surveys and polls, event registration, and issue tracking to measure campaign return on investment and client satisfaction. The company also provides iAPPS Analyzer to manage, measure, and optimize Web properties by recording detailed events and mine data within a Web application for statistical analysis; and iAPPS Rapid Site for building custom Websites. It delivers it s iAPPS product suite through cloud-based software as a service business model or via a traditional perpetual licensing business model. The company?s end-to-end interactive technology solutions consist of digital strategy, user-centered design, Web application development, SharePoint development, rich media development, search engine optimization, and Web application hosting management. Bridgeline Digital serves various markets, such as financial services, consumer products and goods, health services and life sciences, high technology (software and hardware), retail brand names, transportation and storage, associations and foundations, and the U.S. Government through its direct sales force. The company was formerly known as Bridgeline Software, Inc. and changed its name to Bridgeline Digital, Inc. in March 2010. Bridgeline Digital, Inc. was founded in 2000 and is based in Burlington, Massachusetts.

Advisors' Opinion:

• [By Bryan Murphy]

  Congratulations to anyone who owned shares of Bridgeline Digital Inc. (NASDAQ:BLIN) before today. You're now up 35% for the day so far, and still counting. The big pop from BLIN stemmed from the announcement that it scored a pretty significant deal with an organization consisting of nearly 4000 dentists and doctors. The terms of the deal are simple enough... Bridgeline Digital will host and service websites for the practitioners in the group for a period of three years, and in return, BLIN will receive $7 million.